Intravenous vs. left ventricular injection of ionic contrast material: hemodynamic implications for digital subtraction angiography
- 1 March 1983
- journal article
- research article
- Published by American Roentgen Ray Society in American Journal of Roentgenology
- Vol. 140 (3), 425-430
- https://doi.org/10.2214/ajr.140.3.425
Abstract
Because of the increased use of intravenous injection of contrast material for the evaluation of cardiac structure and function by digital subtraction techniques, a study was done to assess the hemodynamic effects of contrast material when used in this fashion in man. In 10 patients, with each serving as his own control, the effects of intravenous and intraventricular injections of sodium meglumine diatrizoate (Renografin 76) in the same dose were compared. There was no difference between these two methods with respect to changes in pulmonary wedge pressures, systemic pressures, and pulmonary vascular resistance. The elevation of mean pulmonary artery and right atrial pressure was greater after the intraventricular injection (p less than 0.05). The elevated cardiac output and systemic vascular resistance returned to control values somewhat more quickly after the intravenous injection (p less than 0.001 and p less than 0.05, respectively); and the increase in cardiac output was greater after the intravenous injection at 1 min (p less than 0.05), but less than after the intraventricular injection at 2 min (p less than 0.05). Despite the detection of these statistically significant differences, the magnitude and timing of these differences are too small to justify the notion that imaging by intravenous injections of standard ionic contrast media provides any substantial hemodynamic benefits or decreased risk to the patient.This publication has 11 references indexed in Scilit:
- Computer enhancement of direct and venous-injected left ventricular contrast angiographyAmerican Heart Journal, 1981
- Immediate effect of contrast medium injection on left ventricular volumes and ejection fraction. A study using metallic epicardial markers.Circulation, 1977
- Hemodynamic effects of rapidly injected hypertonic solutions into the heart and great vesselsAmerican Heart Journal, 1967
- Hemodynamic Consequences of the Injection of Radiopaque MaterialCirculation, 1965
- The Effect of Angiocardiographic Contrast Medium on Circulatory Dynamics in ManCirculation, 1965
- Red Cell Aggregation from Concentrated Saline and Angiographic MediaRadiology, 1964
- Pressor Effect of Hypertonic Saline on Pulmonary CirculationCirculation Research, 1959
- Effect of Hypertonic Saline on the Pulmonary and Systemic PressuresCirculation Research, 1958
- The Physiologic Effect of Contrast Media Used for AngiocardiographyCirculation, 1956
- Blood pressure and heart rate during angiocardiography, abdominal aortography, and arteriography of the lower extremitiesActa Radiologica, 1956