Enzymic Resolution of (± )-Unsaturated Cyclic Terpene AlcoholsviaAsymmetric Hydrolysis of Corresponding Acetates by Microorganisms

Abstract

Asymmetric hydrolysis of the acetates of (±)-cis and trans-carveols by microorganisms or their esterase produced chiral cis and trans-carveols and the acetates of their enantiomers. The enantioselectivity of the microbial hydrolysis and the optical purities of the products varied with the species of microorganisms. This method was also applied in separation of diastereomeric mixtures of (−)-carveols and (−)-7-epi-α-cyperols.