Lack of Effect of Opiates on Release of Vasopressin from Isolated Rat Neurohypophysis
- 1 February 1982
- journal article
- research article
- Published by Wiley in Acta Pharmacologica et Toxicologica
- Vol. 50 (2), 113-116
- https://doi.org/10.1111/j.1600-0773.1982.tb00951.x
Abstract
Electrical stimulation of rat neurohypophysis in vitro results in a 150-fold increase in release of vasopressin. Incubation of the isolated lobes with endogenous opiates (Met-enkephalin, Leu-enkephalin, .beta.-endorphin), morphine or naloxone did not change the evoked release of vasopressin significantly. Endogenous opiates may not inhibit the release of vasopressin from this preparation.Keywords
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