Assessment of Pituitary ACTH Secretory Capacity with Metopirone: II. Comparison with Other Tests1
- 1 September 1963
- journal article
- research article
- Published by The Endocrine Society in Journal of Clinical Endocrinology & Metabolism
- Vol. 23 (9), 953-960
- https://doi.org/10.1210/jcem-23-9-953
Abstract
The Metopirone test has been compared to 2 other measures of pituitary ACTH secretion, the insulin tolerance test and the water-loading test, in a variety of patient groups. The results confirm the impression that the Metopirone test is the most sensitive measure now available for assessing pituitary ACTH secretory capacity. Discrepancies between the Metopirone and insulin tolerance tests were noted, indicating that the Metopirone test should be considered a measure of only one aspect of pituitary ACTH secretory capacity, and not necessarily a measure of total reserve.Keywords
This publication has 9 references indexed in Scilit:
- Assessment of Pituitary ACTH Secretory Capacity with Metopirone: 1. Interpretation1Journal of Clinical Endocrinology & Metabolism, 1963
- DISTURBANCE OF THE PITUITARY-ADRENAL INTERRELATIONSHIP IN DISEASES OF THE CENTRAL NERVOUS SYSTEM*Journal of Clinical Endocrinology & Metabolism, 1961
- CLINICAL USE OF A NEW DIAGNOSTIC AGENT, METHOPYRAPONE (SU-4885), IN PITUITARY AND ADRENOCORTICAL DISORDERSAnnals of Internal Medicine, 1961
- WATER DIURESIS IN ADRENAL CORTICAL INSUFFICIENCYAnnals of Internal Medicine, 1960
- CLINICAL APPLICATION OF A NEW TEST OF PITUITARY RESERVE*Journal of Clinical Endocrinology & Metabolism, 1959
- Mechanisms of Impaired Water Excretion in Adrenal and Pituitary Insufficiency. I. The Role of Altered Glomerular Filtration Rate and Solute Excretion12JCI Insight, 1958
- ALTERATIONS OF ADRENAL STEROID PATTERNS IN MAN RESULTING FROM TREATMENT WITH A CHEMICAL INHIBITOR OF 11 βHYDROXYLATIONJournal of Clinical Endocrinology & Metabolism, 1958
- A CORTISONE-RESISTANT ABNORMALITY IN THE DIURETIC RESPONSE TO INGESTED WATER IN PRIMARY MYXEDEMAJournal of Clinical Endocrinology & Metabolism, 1954
- THE EFFECTS OF INSULIN, HISTAMINE, BACTERIAL PYROGEN, AND THE ANTABUSE-ALCOHOL REACTION UPON THE LEVELS OF 17-HYDROXYCORTICOSTEROIDS IN THE PERIPHERAL BLOOD OF MAN1954