The Size and Distribution of Cytochrome c Oxidase Subunit IV mRNA between Free and Membrane‐Bound Polyribosomes
- 1 September 1981
- journal article
- research article
- Published by Wiley in European Journal of Biochemistry
- Vol. 119 (1), 203-208
- https://doi.org/10.1111/j.1432-1033.1981.tb05595.x
Abstract
A length of 990 .+-. 80 nucleotides was estimated for the poly(A)-rich mRNA of the higher-MW precursor of rat liver cytochrome c oxidase subunit IV. Assuming a MW of 19,500 for the cytochrome c oxidase subunit IV precursor, a non-coding region of .apprx. 350 nucleotides must exist. In experiments on the site of synthesis it is shown that the poly(A)-rich RNA for the high-MW precursor of cytochrome c oxidase subunit IV is found in free, loosely and tightly membrane-bound polyribosomes. This finding does not agree with the present picture of free polysomes as the exclusive site of synthesis for mitochondrial proteins.This publication has 43 references indexed in Scilit:
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