Prolonged Cation-Exchange Resin Therapy in Congestive Heart Failure

Abstract

IN THE past few years increasing clinical interest has been manifested in the ion-exchange resins. These are of two principal types, anion and cation. Anion-exchange resins have been used as antacids and pepsin inhibitors in the management of patients with peptic ulcer.^{1 2 3 4 5 6} Cation-exchange resins are of two common types: sulfonated and carboxylated. Either of these may be saturated with ammonium, hydrogen, potassium or other cations. Their value in the management of congestive heart failure and other related disorders associated with sodium-ion retention and edema is emerging gradually through clinical experience.^{7 8 9 10 11 12 13 14} Dock⁸ in 1946 first suggested that cation-exchange resins might be . . .