Association between HLA and Sjögren's syndrome in Japanese patients
Open Access
- 1 December 1986
- journal article
- research article
- Published by Wiley in Arthritis & Rheumatism
- Vol. 29 (12), 1518-1521
- https://doi.org/10.1002/art.1780291215
Abstract
Japanese patients with primary Sjögren's syndrome (SS), patients with SS and rheumatoid arthritis (SS‐RA), and patients with SS and connective tissue disease without RA (nonrheumatoid connective tissue disease [SS‐CTD]) were typed for HLA antigens. Patients with primary SS and those with SS‐RA had higher frequencies of DRw53 than did those who had SS‐CTD; however, the group with SS‐CTD showed a negative correlation with DRw52. These data indicate that Japanese and white patients with SS have different HLA specificities, and that genetic factors involved in the development of SS‐CTD might be different from those in primary SS and SS‐RA.This publication has 9 references indexed in Scilit:
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