Species Differences in the Utilization of Glucose for Contractile Force by Isolated Perfused Hearts
- 30 December 1954
- journal article
- research article
- Published by American Physiological Society in American Journal of Physiology-Legacy Content
- Vol. 180 (1), 103-106
- https://doi.org/10.1152/ajplegacy.1954.180.1.103
Abstract
The effects of glucose, 200 mg/100 cc, were studied on 12 substrate depleted hearts of cats, rabbits, guinea pigs and rats. Rat hearts showed an average increase in contractile force equal to 51% of the original control before failure. The increases shown by the guinea pig, rabbit, and cat hearts were 12, 8 and 4%, respectively. Rate and coronary flow were unchanged. These results indicate the importance of spp. differences in evaluating the utilization of substrates by the heart.Keywords
This publication has 3 references indexed in Scilit:
- THE AUGMENTING EFFECT OF THE PRESSOR HORMONE OF PITUITARY EXTRACT UPON THE CONTRACTION OF THE ISOLATED PERFUSED MAMMALIAN HEART - THE BEARING OF CORONARY FLOW ON HEART CONTRACTION1951
- METABOLISM OF THE HEART IN RELATION TO DRUG ACTION. IV. EFFECTS OF VARIOUS SUBSTRATES UPON THE ISOLATED PERFUSED RAT HEARTAmerican Journal of Physiology-Legacy Content, 1949
- Untersuchungen am überlebenden SäugethierherzenPflügers Archiv - European Journal of Physiology, 1895