Granulomatous Peritonitis Secondary to Corn Starch

Abstract

A case of granulomatous peritonitis secondary to corn starch glove powder is described. It is believed to represent the fifteenth symptomatic case to be reported in the English language, the second to be treated with corticosteroids, and the first to show hypersensitivity demonstrable by skin test. A review of the reported cases reveals a syndrome manifested clinically by evidence of peritoneal inflammation or bowel obstruction, developing 2 to 6 weeks postoperatively. Pathological characteristics include ascites, miliary nodules, and adhesions. Microscopic examination reveals chronic inflammation with granuloma formation, and starch particles are readily demonstrable under polarized light. Long-term prognosis appears good. Other types of reported reactions in man and the pertinent experimental work are reviewed. The need for meticulous cleansing of surgical gloves is emphasized.