EINE FORM VON DAUEROESTRUS BEI DER MAUS UND IHRE DEUTUNG AUS DEM FUNKTIONSVERHÄLTNIS HYPOPHYSE-GONADE

Abstract

Among the females of a strain of albino mice with a particularly heavy weight were found animals in constant estrus not identical with the spontaneous or experimentally produced constant estrus described in the literature for the rat. It was concluded that the persistent estrus was due to a cyclical but excessive release of follicle stimulating hormone and lutenizing hormone by the hypophysis. All agents except implantation of testes and injections of testosterone propionate and of Pentothal failed to interrupt the persistent estrus. It was suggested that these agents acted by depressing the release of gonadotropins by the hypophysis.