Regulation of phosphodiesterase and ornithine decarboxylase by cAMP is cell cycle independent
- 1 December 1979
- journal article
- research article
- Published by Wiley in Journal of Cellular Physiology
- Vol. 101 (3), 369-374
- https://doi.org/10.1002/jcp.1041010304
Abstract
Cyclic AMP (cAMP) causes growth arrest in G1 and induction of cAMP phosphodiesterase and decrease of ornithine decarboxylase in S49 mouse lymphoma cells. Dibutyryl cAMP treatment of partially synchronized cells causes similar changes in activities of both enzymes, regardless of position in the cell cycle. This suggests that cAMP regulation of these enzymes is not mediated by growth perturbation.This publication has 8 references indexed in Scilit:
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