Pulmonary stenosis, cafe-au-lait spots, and dull intelligence.

Abstract

Of 17 children in 3 unrelated sibships, 12 had multiple cafe-au-lait spots inherited from a parent, and 8 of the 12 had pulmonary valvular stenosis. Most of the children were dull. There is a significant association between pulmonary valvular stenosis, cafe-au-lait spots and a dull intelligence.