125I-Anti-Immunoglobulin Test: A New Tool for the Detection of Drug-Allergic Platelet Antibodies

Abstract

It is shown that the ¹²⁵I-anti-immunoglobulin test with platelets is as sensitive and reproducible for the detection of quinidine-associated antibodies as platelet complement fixation. Because of its independence from complement activation, this test might prove most valuable for the demonstration of non-complement-fixing, drug-associated antibodies.