DOES SODIUM NITROPRUSSIDE IMPROVE TISSUE OXYGENATION DURING CARDIOPULMONARY BYPASS ?

Abstract

Patients (8) undergoing cardiopulmonary bypass with hypothermia received, during part of the hypothermic phase, an infusion of sodium nitroprusside (SNP). O2 consumption was measured during the infusion and during control periods. Despite causing a marked reduction of arterial pressure, SNP was not shown to have any significant effect upon whole-body O2 consumption or lactate concentration in the blood.