Towards a quantitative representation of the cell signaling mechanisms of hallucinogens: Measurement and mathematical modeling of 5-HT1A and 5-HT2A receptor-mediated ERK1/2 activation
- 31 December 2009
- journal article
- Published by Elsevier in Neuropharmacology
- Vol. 56 (Suppl 1), 213-225
- https://doi.org/10.1016/j.neuropharm.2008.07.049
Abstract
No abstract availableKeywords
This publication has 71 references indexed in Scilit:
- Active State-like Conformational Elements in the β2-AR and a Photoactivated Intermediate of Rhodopsin Identified by Dynamic Properties of GPCRsBiochemistry, 2008
- Protein Diffusion on Charged Membranes: A Dynamic Mean-Field Model Describes Time Evolution and Lipid ReorganizationBiophysical Journal, 2008
- Identification of a serotonin/glutamate receptor complex implicated in psychosisNature, 2008
- Universally Sloppy Parameter Sensitivities in Systems Biology ModelsPLoS Computational Biology, 2007
- Hallucinogen actions on 5-HT receptors reveal distinct mechanisms of activation and signaling by G protein-coupled receptorsThe AAPS Journal, 2005
- Enhanced activation of Akt and extracellular‐regulated kinase pathways by simultaneous occupancy of Gq‐coupled 5‐HT2A receptors and Gs‐coupled 5‐HT7A receptors in PC12 cellsJournal of Neurochemistry, 2004
- Signaling Life and Death in the Thymus: Timing Is EverythingScience, 2003
- KSR modulates signal propagation within the MAPK cascade.Genes & Development, 1996
- The two-state model of receptor activationTrends in Pharmacological Sciences, 1995
- G PROTEINS: TRANSDUCERS OF RECEPTOR-GENERATED SIGNALSAnnual Review of Biochemistry, 1987