THE SEDIMENTATION RATE OF THE BIOLOGICAL ACTIVITIES OF INFLUENZA A VIRUS
Open Access
- 1 December 1944
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 80 (6), 521-529
- https://doi.org/10.1084/jem.80.6.521
Abstract
The sedimentation rates of the mouse infectivity principles of the PR8 and the F12 strains of influenza A virus were shown by studies in the separation cell to have values which are not significantly different from sedimentation rates of the principal components of purified preparations. It was shown further that the bulk of the chicken red blood cell agglutinating activity and of the chick embryo infectivity of PR8 influenza virus preparations sediments at the same rate as that of the 100 mµ. component. Some activity was shown to be associated with aggregates. These results lend strong support to the assumption that the three biological activities are associated with the particles characterized as spheres with a diameter of about 100 mµ.This publication has 13 references indexed in Scilit:
- TITRATION OF INFLUENZA VIRUS IN CHICK EMBRYOSThe Journal of Experimental Medicine, 1944
- CENTRIFUGATION AND ULTRAFILTRATION STUDIES ON ALLANTOIC FLUID PREPARATIONS OF INFLUENZA VIRUSThe Journal of Experimental Medicine, 1944
- THE SIZE OF INFLUENZA VIRUSThe Journal of Experimental Medicine, 1944
- THE MOUSE INFECTIVITY TITRATION OF INFLUENZA VIRUSThe Journal of Experimental Medicine, 1944
- QUANTITATIVE ASPECTS OF THE RED BLOOD CELL AGGLUTINATION TEST FOR INFLUENZA VIRUSThe Journal of Experimental Medicine, 1944
- A STUDY OF CONDITIONS FOR THE OPTIMUM PRODUCTION OF PR8 INFLUENZA VIRUS IN CHICK EMBRYOSThe Journal of Experimental Medicine, 1944
- Isolation and Characterization of Influenza Virus B (Lee Strain)Science, 1943
- STUDIES ON THE NATURE OF THE VIRUS OF INFLUENZAThe Journal of Experimental Medicine, 1943
- The Agglutination of Red Cells by Allantoic Fluid of Chick Embryos Infected with Influenza VirusScience, 1941
- AN IMPROVED AIR-DRIVEN TYPE OF ULTRACENTRIFUGE FOR MOLECULAR SEDIMENTATIONThe Journal of Experimental Medicine, 1937