We describe the use of 3-dimensional, multiplanar ultrasound imaging for peripheral nerve block. To illustrate the potential usefulness of the technique, we present a case in which real-time 3-dimensional, multiplanar ultrasound was used to assist in the performance of a radial nerve block. Three-dimensional, multiplanar ultrasound in real-time has the potential to improve nerve identification and accuracy of needle placement in regional anesthesia.