The flexion deformity of the wrist and fingers resulting from contraction and fibrosis of the flexor muscles of the forearm, which is known as Volkmann's ischemic contracture, is of especial interest (fig. 1). Affecting children and occurring as a complication of fractures of the lower end of the humerus, it results in permanent partial or total disability when once it is established despite the most expert surgical and physical treatment. It is of interest to note that in the articles and reports of cases published since the original report of Volkmann in 1869 no author has claimed a certain method of cure. While there has been some difference of opinion, in the past, as to the factors involved in the production of the contracture, we at the Mayo Clinic believe that the etiology is now readily understood and that the means of prevention are available. To those who will carefully