Demonstration of Y/autosomal translocations using distamycin A
- 1 January 1979
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 53 (1), 107-109
- https://doi.org/10.1007/bf00289459
Abstract
The condensation of the brightly fluorescing Y-heterochromatin is prevented by cultivating leukocytes in a medium containing distamycin A. This technique provides a reliable method for the identification of those Y/autosomal translocations in which Y heterochromatin is involved. A case of a familiar Y/22 translocation and the distamycin A technique are described.Keywords
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