Metachromatic agar-diffusion methods for detecting staphylococcal nuclease activity.

  • 1 April 1971
    • journal article
    • Vol. 21 (4), 585-7
Abstract
Based on the metachromatic property of Toluidine Blue O, three, convenient agar-diffusion methods have been developed that enable detection of the nuclease of Staphylococcus aureus at concentrations as low as 0.005 mug/ml in agar and broth cultures. The interactions of agar and deoxyribonucleic acid with Toluidine Blue O are discussed.