Deamidation of Insulin during Storage in Frozen State
- 1 December 1966
- journal article
- research article
- Published by American Diabetes Association in Diabetes
- Vol. 15 (12), 875-879
- https://doi.org/10.2337/diab.15.12.875
Abstract
Insulin dissolved in weakHCl (5x10-3 [image]) appears to undergo progressive deamidation on storage at[long dash]15[degree] C Some commercial solutions of insulin contain quite significant amounts of desamido components. The possibility that desamido insulin may contribute to insulin antigenicity is considered.This publication has 2 references indexed in Scilit: