Acanthosis Nigricans

Abstract

ACANTHOSIS nigricans associated with cancer of the thyroid gland has apparently never been recorded in human beings. The following case is therefore of particular interest.A 33-year-old Negress was admitted to the Surgical Service of the University of Virginia Hospital on February 1, 1947, complaining of shortness of breath of 1 month's duration.In December, 1944, the patient had had a rapid onset of tremulousness, palpitation, dysphagia, exertional dyspnea, progressive weight loss and painless tumor formation in the anterior portion of the neck. On February 26, 1945, she had been admitted to another hospital, where the thyroid gland was found . . .