Defective Monocyte Function in Patients With Genitourinary Carcinoma 2

Abstract

An assay allowing quantitation of monocyte function, i.e., chemotaxis, was used to study the activity of monocytes in patients with neoplasms of the urinary tract. Twenty-four subjects with various stages of renal carcinoma exhibited a mean chemotactic defect of 34% (PP<0.01) mean chemotactic defect as compared to the controls. There was no correlation between tumor stage and degree of chemotactic defect.