Pellagrins in relapse are benefited by treatment with nicotinic acid and adenylic acid. 6 patients with malnutrition, who had intense burning of the oral mucous membranes, but no diagnostic evidence of pellagra, were relieved following treatment with adenylic acid alone. Since severe reactions were produced by the intraven. injection of 3 preps. of adenylic acid, this compound should not be administered to human beings.