On the effects of beta rays from radium upon division and growth of cancer cells

Abstract

The authors contend that cells of the Jensen''s rat sarcoma suffer no immediate recognizable change after exposure to large doses of beta rays. The absence of dividing cells in subsequent stages is due to a temporary inhibition of division of maturing cells. The final changes which occur in exposed J.R.S. cells are profound enough to prevent growth of the tumor when inoculated. The daughter cells are no longer capable of undergoing normal division.