Impairment of Hormone Dependent Signal Transfer by Chronic SSPE Virus Infection
- 1 March 1979
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 42 (3), 615-619
- https://doi.org/10.1099/0022-1317-42-3-615
Abstract
In a CNS[central nervous system]-derived [glioma C-6] cell line, the cellular response to hormonal [isoproterenol] stimulation, represented by the rise of intracellular c[cyclic]AMP levels, is impaired under the influence of a persisting neurotropic virus infection. This dysfunction is caused by the decrease in adenylate cyclase activity, most probably due to the virus-induced loss of active catalytic units.This publication has 1 reference indexed in Scilit:
- Biological and biochemical characterization of a latent subacute sclerosing panencephalitis (SSPE) virus infection in tissue cultureJournal of Medical Virology, 1977