MECHANISM OF OVULATION IN THE RABBIT

Abstract
It has been impossible to produce ovulation in the rabbit by the transplantation of as many as 15 fresh rat hypophyses, or by the intraperitoneal injection of 24 fresh rat hypophyses. Intraperitoneal injection of urine from pregnant women produces luteinization of the resulting corpora hemorrhagica in the rabbit ovary. A single intravenous injection of urine from pregnant women provokes ovulation in the rabbit. The samples of urine so far obtained from non-pregnant women have been utterly without effect on the rabbit ovary when injected intraperitoneally or intravenously.

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