Localization of HLA on the short arm of chromosome 6
- 1 January 1977
- journal article
- research article
- Published by Springer Nature in Human Genetics
- Vol. 37 (2), 131-139
- https://doi.org/10.1007/bf00393575
Abstract
A detailed marker gene study in a large Dutch kindred segregating for a reciprocal translocation between the chromosomes 6 and 20, t(6;20) (p21;p13), revealed a close linkage between the HLA genes and the breakpoint on the short arm of 6. During this study an apparent peak lod score of 2.9 was obtained at a recombination value of 0.05 for a linkage between HLA and the breakpoint, indicating that the chromosomal region, carrying the HLA genes, is situated near the breakpoint in band 6p21 close to the transition to 6p22.This publication has 25 references indexed in Scilit:
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