Chediak’s Anomaly of Leukocytes in Malignant Lymphoma Associated with Leukemic Manifestations: Case Report with Necropsy

Abstract

A case of Chediak’s anomaly of leukocytes was described, the fourth reported in the literature. The patient was an 11-month-old boy who, in addition to Chediak’s anomaly of the leukocytes, presented a leukemic blood picture. He died five days after admission to the hospital, and necropsy revealed a malignant lymphoma. We consider it possible that in all the reported cases there were generalized pathologic changes in the reticulohistiocytic system.