ATP and GTP as alternative energy sources for vinblastine transport by P‐170 in KB‐V1 plasma membrane vesicles
- 15 June 1992
- journal article
- Published by Wiley in FEBS Letters
- Vol. 304 (2-3), 256-260
- https://doi.org/10.1016/0014-5793(92)80632-q
Abstract
Purified plasma membrane vesicles isolated from multidrug‐resistant human KB‐V1 cells accumulate [3H]vinblastine in an energy‐dependent manner. The accumulation of [3H]vinblastine in the presence of ATP is a saturable process. ATP can be replaced by other purine nucleotide triphosphates, of which GTP is the most efficient.This publication has 16 references indexed in Scilit:
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