Microchemical Architecture of Human Isocortex
- 1 April 1967
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Neurology
- Vol. 16 (4), 351-356
- https://doi.org/10.1001/archneur.1967.00470220015002
Abstract
DEFINITIVE knowledge of the biochemistry of cerebral cortex is not commensurate with that of its microscopic anatomy or neurophysiological properties. This can partly be attributed to the relatively delayed development of neurochemistry as a whole, and especially of a precise methodology for detailed study of its molecular organization. However, the pioneering development of quantitative histochemistry by K. Linderstrøm-Lang and H. Holter of the Carlsberg Laboratories in Copenhagen and the systematic elaborations and refinements thereof due particularly to two of their distinguished American students, O. H. Lowry and D. Glick, have provided the requisite technology for microneurochemistry. These developments, in turn, have enabled investigations on the molecular and enzymatic architecture of numerous anatomical substituents of mammalian brain including the cerebral cortex of the rat,1-5 rabbit,6 and monkey.7,8 There is, nevertheless, a particular lack of systematic information concerning the biochemistry of the cortex of man inThis publication has 11 references indexed in Scilit:
- MICROASSAY OF BIOCHEMICAL STRUCTURAL COMPONENTS IN NERVOUS TISSUES–IIJournal of Neurochemistry, 1965
- MICROASSAY OF BIOCHEMICAL STRUCTURAL COMPONENTS IN NERVOUS TISSUES–IJournal of Neurochemistry, 1965
- INTRALAMINAR DISTRIBUTION OF Na+‐K+ ADENOSINE TRIPHOSPHATASE IN RAT CORTEXJournal of Neurochemistry, 1964
- INTRALAMINAR DISTRIBUTION OF ADENOSINETRI‐PHOSPHATASE ACTIVITY IN HUMAN FRONTAL ISOCORTEX*Journal of Neurochemistry, 1961
- INTRALAMINAR DISTRIBUTION OF CYTOCHROME OXIDASE ACTIVITY IN HUMAN FRONTAL ISOCORTEX*Journal of Neurochemistry, 1960
- THE INTRALAMINAR DISTRIBUTION OF DIPEPTIDASE ACTIVITY IN HUMAN FRONTAL ISOCORTEX*Journal of Neurochemistry, 1959
- INTRALAMINAR DISTRIBUTION OF CYTOCHROME OXIDASE AND DPN IN RAT CEREBRAL CORTEXJournal of Neurophysiology, 1956
- THE QUANTITATIVE HISTOCHEMISTRY OF BRAIN .3. AMMONS HORN1954
- QUANTITATIVE DISTRIBUTION OF DIPEPTIDASE AND ACETYLCHOLINE ESTERASE IN ARCHITECTONIC LAYERS OF RAT CEREBRAL CORTEXJournal of Neurophysiology, 1952
- PROTEOLIPIDES, A NEW TYPE OF TISSUE LIPOPROTEINS - THEIR ISOLATION FROM BRAIN1951