A METHOD OF GAS CHROMATOGRAPHY USING ELECTRON-CAPTURE DETECTION FOR THE DETERMINATION OF BLOOD CONCENTRATIONS OF HALOTHANE, CHLOROFORM AND TRICHLOROETHYLENE
A method of gas chromatography using electron-capture detection for the determination of the concentration of the halogenated anaesthetic agents halothane, chloroform and trichloroethylene in blood is described. The accuracy of the analysis (measured blood concentration as a percentage of the calculated concentration) was: Halothane (11 blood samples in the range 37.9–6.00 mg/100 ml), mean 100.7 (SD 2.27), range 97.3–104.0; (12 samples in the range 0.164–0.0045 mg/100 ml), mean 98.8 (SD 6.80), range 90.7–111.1. Chloroform (five blood samples in the range 63.6–7.40 mg/ 100 ml), mean 100.4 (SD 1.30), range 99.3–102.5. Trichloroethylene (five blood samples in the range 20.6–13.2 mg/100 ml), mean 101.6 (SD 1.60), range 99.6–104.0.