During recent years, many articles relating to pathologic lesions of the thyroid gland have appeared in the literature, but intrathoracic goiter has received scant attention. It is with the hope of contributing something to the solution of the various problems presented by this condition that I am offering this analysis of 100 cases of complete intrathoracic goiter, together with a review of the literature. GENERAL REVIEW OF THE LITERATURE Attention was first focused on this condition between the years 1912 and 1916, during which period an occasional article or case report was presented in the foreign literature. Since that time, articles have appeared from time to time in both American and foreign journals. In 1914, Key1 described two cases of intrathoracic goiter in which operation was performed by the Sauerbruch-Schoemaker technic (resection of part of the sternum). In 1917, Lahey2 described the mechanism of the production of intrathoracic