DEXTRANS AND GLYCOGENS AS PARTICULATE TRACERS FOR STUDYING CAPILLARY PERMEABILITY
Open Access
- 1 September 1971
- journal article
- Published by Rockefeller University Press in The Journal of cell biology
- Vol. 50 (3), 616-624
- https://doi.org/10.1083/jcb.50.3.616
Abstract
Commercially available glycogens and dextrans can be used as biological particulate tracers in work on capillary permeability. These polysaccharides are well tolerated in intravenous injection and induce no vascular leakage when applied topically (cremaster test) in mice and in Wistar-Furth rats. The particles stain adequately with lead after aldehyde-OsO(4) fixation in phosphate buffer and provide a relatively wide set of probes ( approximately 45 A-300 A) for work on the large and small pore systems.Keywords
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