Abstract
A quantitative study of the diluting power of the kidneys, based on 31 water-loading experiments in 10 normal men, is reported. A minimum urine total solute concentration (MUC) of 59 mOs/l. was observed, with a range of 37 to 80 mOs/l. The MUC appears to be independent of the size of the water load when the load exceeds a minimum level (1000–1500 ml). Further increase in water intake only extends the period of minimum urine total solute concentration. Submitted on September 4, 1956