THE TEMPORARY NATURE OF THE INHIBITORY ACTION OF EXCESS IODIDE ON ORGANIC IODINE SYNTHESIS IN THE NORMAL THYROID1
- 1 November 1949
- journal article
- research article
- Published by The Endocrine Society in Endocrinology
- Vol. 45 (5), 504-513
- https://doi.org/10.1210/endo-45-5-504
Abstract
Expts. designed to test the duration of inhibition, by excess iodide, of organic binding of I in the thyroid gland are descr. The inhibitory action of excess iodide on the normal rat thyroid is temporary. Inhibition lasted for about 26 hrs. Despite the continued maintenance of a high level of plasma total I (100-200 [mu]g. %), the formation of significant amts. of organic I was resumed after 26 hrs.Keywords
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