METABOLISM OF MAMMALIAN ERYTHROCYTES: VII. THE GLUTATHIONE REDUCTASE OF THE MAMMALIAN ERYTHROCYTE

Abstract

In the presence of the stroma-free hemolyzate of rat, rabbit, and human erythrocytes, GSSG has been shown to be reduced by G-6-P and TPN⁺, HDP and DPN⁺, or by chemically reduced TPNH and DPNH. Evidence has been presented that DPNH–GSSG reductase requires a cofactor for full activity.