Relationship between serotypes, dermonecrotic toxin production of Pasteurella multocida isolates and pneumonic lesions of porcine lung.

Abstract

A total of 116 Pasteurella multocida isolates from pneumonic lesions of porcine lungs with consolidation, abscess and pleuritis between 1983 and 1986 in Nagasaki Prefecture of Japan were determined for their serotypes and dermonecrotic toxin (DNT) productivity. Of them, 95 isolates (81.9%) belonged to capsular serotype A, and the remaining 21 ones (18.1%) to serotype D. A correlation was found between capsular serotype and lung lesion, such as serotype D strains were isolated only from abscesses, not from consolidation and pleuritis. In somatic serotype, most isolates (94.0%) had type 3 antigen. Twenty-one isolates (18.1%) were DNT positive and all of them were isolated from abscesses. Serotypes of the DNT positive isolates were D:3 (61.9%), A:3.4 (14.3%), D:11 (9.5%), D:3.7 (4.8%), D:3.4.7.12 (4.8%) and D:7.12 (4.8%).