Correlation of Preoperative Immunologic Test Results with Recurrence in Patients with Head and Neck Cancer
- 1 January 1980
- journal article
- Published by Wiley in Otolaryngology -- Head and Neck Surgery
- Vol. 88 (1), 58-63
- https://doi.org/10.1177/019459988008800116
Abstract
IgA immunoglobulin fractions containing antibodies to Epstein-Ban virus (EBV)-induced membrane antigens were isolated from the sera of two patients with nasopharyngeal carcinoma (NPC), from one non-NPC patient, and from three persons with sera negative for IgA antibodies. IgA antibodies were not cytotoxic against cells expressing EBV-induced membrane antigens in the antibody-dependent cellular cytotoxicity (ADCC) assay. However, IgA antibodies blocked IgG-mediated ADCC, which indicated that these antibodies could serve as a blocking “factor” in patients with disease and, therefore, were potentially detrimental to the host.Keywords
This publication has 11 references indexed in Scilit:
- Nonspecific immune determinants in the patient with unresectable gastrointestinal carcinomaCancer, 1979
- A prospective study of immune responsiveness in human melanoma.I. Assessment of initial pretreatment status with stage of diseaseCancer, 1978
- T-lymphocytes and Survival of Head and Neck Squamous Cell CarcinomaJAMA Otolaryngology–Head & Neck Surgery, 1977
- T-cell deficiency in patients with squamous cell cancer of the head and neckThe American Journal of Surgery, 1975
- T-lymphocyte levels in the peripheral blood of patients with cancer of the head and neckThe American Journal of Surgery, 1975
- Studies of Mitogen-induced Lymphocyte Transformation by a Semi-microtechnicAmerican Journal of Clinical Pathology, 1975
- Identification, Enumeration, and Isolation of B and T Lymphocytes from Human Peripheral BloodScandinavian Journal of Immunology, 1974
- Immunocompetence in Advanced Cancer Patients prior to ChemotherapyOncology, 1974
- A Method for Dinitrochlorobenzene Contact SensitizationNew England Journal of Medicine, 1972
- ELICITATION OF DELAYED ALLERGIC SKIN REACTIONS WITH HAPTENS: THE DEPENDENCE OF ELICITATION ON HAPTEN COMBINATION WITH PROTEINThe Journal of Experimental Medicine, 1952