INVERSION DUPLICATION OF CHROMOSOME-6 WITH TRISOMIC CO-DOMINANT EXPRESSION OF HLA ANTIGENS

  • 1 January 1979
    • journal article
    • research article
    • Vol. 31 (1), 29-34
Abstract
Trisomic codominant expression of the HLA antigens was observed in a [grossly abnormal] infant with duplication of a part of 6p occurring as a result of crossing over within a paternally transmitted pericentric inversion. The HLA-A and B loci were linked absolutely with the inversion chromosome in a 4 generation pedigree.