The Induction of Micronuclei in Human Lymphocytes byin VitroIrradiation with Alpha Particles from Plutonium-239

Abstract
Human peripheral blood lymphocytes were irradiated for 24 h in vitro with plutonium-239 citrate. The dose response for micronucleus induction using the cytochalasin B blocking technique fitted well to a linear relationship. Comparison with published data from the same laboratory using X-irradiation, indicated an RBE of 3·6 for alpha particles at low doses.

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