S35 Taurine Metabolism in Normal and Mongoloid Individuals.

Abstract

Summary The metabolism of S³⁵ taurine has been studied in normal individuals and mongols. The latter contains a group that excretes very low amounts of urinary taurine and urine from these individuals yields radiograms similar to those obtained from fasting normal individuals. These radiograms are characterized by the appearance of taurine metabolites in relatively greater amounts than taurine itself. In contrast, normal individuals after a meal produce patterns characterized by large taurine peaks compared to taurine metabolites. When administered loads of taurine, the low excretors among the mongols excrete much less of the load than do higher excretors. The low excretors behave as if deficient in body taurine.