MurQ Etherase Is Required by Escherichia coli in Order To Metabolize Anhydro- N -Acetylmuramic Acid Obtained either from the Environment or from Its Own Cell Wall
- 15 February 2006
- journal article
- research article
- Published by American Society for Microbiology in Journal of Bacteriology
- Vol. 188 (4), 1660-1662
- https://doi.org/10.1128/jb.188.4.1660-1662.2006
Abstract
MurQ is an N-acetylmuramic acid-phosphate (MurNAc-P) etherase that converts MurNAc-P to N-acetylglucosamine-phosphate and is essential for growth on MurNAc as the sole source of carbon (T. Jaegar, M. Arsic, and C. Mayer, J. Biol. Chem. 280:30100-30106, 2005). Here we show that MurQ is the only MurNAc-P etherase in Escherichia coli and that MurQ and AnmK kinase are required for utilization of anhydro-MurNAc derived either from cell wall murein or imported from the medium.Keywords
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