Reversal of Morphine Tolerance after Medial Thalamic Lesions in the Rat
- 2 August 1974
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 185 (4149), 449-451
- https://doi.org/10.1126/science.185.4149.449
Abstract
Tolerance, manifested by a diminished electroencephalographic response at cortical and subcortical recording sites, was found in rats subjected to repeated systemic injections of morphine sulfate. Reversal of tolerance to morphine resulted from destruction of the medial thalamus.Keywords
This publication has 3 references indexed in Scilit:
- Properties of Opiate-Receptor Binding in Rat BrainProceedings of the National Academy of Sciences, 1973
- Evidence for Active Immunity to Morphine in MiceScience, 1972
- Neuroanatomical Correlates of Morphine DependenceScience, 1972