PROGESTERONE EFFECTS ON GALACTOSE METABOLISM IN PREPUBERTAL PATIENTS WITH CONGENITAL GALACTOSEMIA AND IN RATS MAINTAINED ON HIGH GALACTOSE DIETS*
Open Access
- 1 January 1960
- journal article
- research article
- Published by American Society for Clinical Investigation in JCI Insight
- Vol. 39 (1), 178-184
- https://doi.org/10.1172/jci104017
Abstract
Administration of progesterone to 3 prepubertal patients with congenital galactosemia resulted in a significant increase in ability to oxidize a tracer dose of galactose-1-C14 to C14O2. Furthermore, administration of progesterone to young male rats maintained on high galactose diets causes a delay in the onset and a decrease in the daily incidence of cataract formation.Keywords
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