Specific Interaction of Feline Immunodeficiency Virus Surface Glycoprotein with Human DC-SIGN
Open Access
- 1 March 2004
- journal article
- Published by American Society for Microbiology in Journal of Virology
- Vol. 78 (5), 2597-2600
- https://doi.org/10.1128/jvi.78.5.2597-2600.2004
Abstract
DC-SIGN, a specific C-type lectin expressed on dendritic cells, binds and transmits multiple strains of primate immunodeficiency viruses to susceptible cells. Here, we report that human DC-SIGN also captures feline immunodeficiency virus via high-affinity (1 nM), Ca2+-dependent,d-mannose-inhibited binding to the major envelope glycoprotein, gp95.Keywords
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