Cimetidine in the prevention of gastric ulcer relapse
- 1 June 1979
- journal article
- clinical trial
- Published by Oxford University Press (OUP)
- Vol. 55 (644), 393-395
- https://doi.org/10.1136/pgmj.55.644.393
Abstract
Summary: Twenty-five patients with healed gastric ulcers completed an 11-month double-blind controlled trial comparing cimetidine 1 g daily with placebo in the prevention of ulcer relapse. Ulcers recurred in 14 patients, 12 on placebo, 2 on cimetidine. In 11 patients, 9 on cimetidine, 2 on placebo, the ulcers remained healed at the end of the trial (P < 0.002). Cimetidine 1 g daily significantly reduces the relapse rate in gastric ulceration.Keywords
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