Estimation of Absolute Entropies From Gas Chromatographic Retention Data

Abstract

Absolute entropies of compounds in homologous series have been found to be directly related to the logarithm of the adjusted retention volumes obtained from gas-liquid chromatographic measurements. Different liquid substrates and column temperatures have been employed in the collection of retention data for homologous series of hydrocarbons, ketones and alcohols and shown to be related to absolute entropies. The retention volume method can be employed as a fast and relatively inexpensive way of predicting absolute entropies of organic compounds.