Photoreactivation of Ultraviolet-Induced Chromosomal Aberrations
- 5 January 1973
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 179 (4068), 86-88
- https://doi.org/10.1126/science.179.4068.86
Abstract
Ultraviolet induces only chromatid-type aberrations in synchronized G1 V-79 Chinese hamster and A8W243 Xenopus tissue culture cells. Posttreatment with white light prevents expression of most potential aberrations in the A8 toad cell, which possesses a photoreactivation enzyme. We conclude that the major ultraviolet-induced DNA lesion leading to chromosomal aberrations is the pyrimidine dimer.Keywords
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