Inhibition of cholinergic response by taurine in frog isolated skeletal muscle
- 1 January 1984
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 36 (1), 59-61
- https://doi.org/10.1111/j.2042-7158.1984.tb02991.x
Abstract
Carbamylcholine-stimulated contractions of isolated frog gastrocnemius muscle were inhibited in a non-competitive fashion by 5–25 mm taurine. Taurine had no effect on the resting length of the muscle. Caffeine-induced contractures were unaffected by taurine which indicates that the sarcoplasmic reticulum is not an important site of action for taurine. A possible functional role for taurine in skeletal muscle is discussed.Keywords
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